Author
Janssen (Belgium)
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Johan Fredin Haslum, Charles-Hugues Lardeau, Johan Karlsson…·Erik Müllers
This study uses deep learning on Cell Painting data to predict compound bioactivity, improving hit rates and diversity in high-throughput screening.
Beth A. Cimini, Srinivas Niranj Chandrasekaran, Maria Kost‐Alimova…·Anne Elizabeth Carpenter
The paper updates the Cell Painting assay protocol to improve morphological profiling, finding that simplified steps and reduced stain concentrations maintain robust outputs.
Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix…·Anne Elizabeth Carpenter
Cell Painting images and profiles for 115,796 compounds in U2OS cells from 12 laboratories; 15.2% of analyzed compounds are phenotypically active, and cross-laboratory replicates cut reference-compound activity by 34%.
Michel Owusu, Peter Bannauer, Joana Ferreira da Silva…·Joanna I. Loizou
The paper identifies kinase-specific vulnerabilities and resistances in response to DNA damaging agents using kinase-deficient cell lines and validates gene-drug interactions.