BiophysicsbioRxiv
The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins
Charlotte Nixon, Shion A. Lim, Matt Sternke…·Susan Marqusee
The paper compares consensus and ancestral protein reconstruction methods using Ribonuclease H sequences, finding that phylogenetically restricted consensus proteins are more stable than those from diverse clades.
DOI 10.1002/pro.5011