Developmental BiologybioRxivPreprint
Positive feedback loop of regulating ERK phosphorylation in mESCs mediated by Etv5-Tet2-Fgfr2 axis
Chen Fan, Kui Zhu, Yuan Liu…·Shiqiang Zhang
The paper identifies a positive feedback loop regulating ERK phosphorylation in mESCs through the Etv5-Tet2-Fgfr2 axis, showing Etv5 influences Fgfr2 expression via Tet2-mediated DNA methylation.
DOI 10.1101/560334