Cancer BiologybioRxivPreprint
Patient-derived tumor organoids from resected non-small cell lung cancers for high-throughput response testing with approved and repurposed drugs
Kanve N. Suvilesh, Yariswamy Manjunath, Yulia I. Nussbaum…·Jussuf T. Kaifi
This study develops patient-derived tumor organoids from non-metastatic NSCLC tumors to test drug responses and identify chemoresistance mechanisms, finding 50% of organoids were chemo-resistant and could be sensitized by repurposed drugs.
DOI 10.1101/2023.10.18.562944