Jussuf T. Kaifi

This paper characterizes a bronchoscopically induced transgenic lung cancer pig model, showing high translatability to human lung cancer with significant transcriptome overlap.

This study develops ExoFeR, a system combining extracellular vesicles and iron oxide nanoparticles, to induce ferroptosis and overcome cisplatin resistance in lung cancer cells.

This study shows red cabbage juice modulates gut microbiota to improve intestinal homeostasis and reduce colitis in mice by enhancing SCFA production and suppressing inflammatory pathways.

This study develops patient-derived tumor organoids from non-metastatic NSCLC tumors to test drug responses and identify chemoresistance mechanisms, finding 50% of organoids were chemo-resistant and could be sensitized by repurposed drugs.