Yariswamy Manjunath

This paper characterizes a bronchoscopically induced transgenic lung cancer pig model, showing high translatability to human lung cancer with significant transcriptome overlap.

This study develops ExoFeR, a system combining extracellular vesicles and iron oxide nanoparticles, to induce ferroptosis and overcome cisplatin resistance in lung cancer cells.

This study develops patient-derived tumor organoids from non-metastatic NSCLC tumors to test drug responses and identify chemoresistance mechanisms, finding 50% of organoids were chemo-resistant and could be sensitized by repurposed drugs.