ImmunologybioRxivPreprint
Fibroblast orchestration of inflammaging via NF-kB activation
Nancy C. Allen, Christian Ringler, Jin Young Lee…·Tien Peng
This study shows that aged fibroblasts activate NF-kB, leading to immune changes like exhausted T cells, autoimmunity, and cancer, increasing susceptibility to age-related diseases.
DOI 10.1101/2025.10.01.679697