Molecular BiologybioRxivPreprint
The cancer-promoting enzyme PKM2 binds RNA via a positively charged regulatory patch
Pia Sommerkamp, Christian Schillinger, Karine Lapouge…·Matthias W. Hentze
This study shows PKM2 binds RNA through a positively charged surface patch, with RNA binding influenced by its oligomeric state and allosteric regulator FBP.
DOI 10.64898/2026.09.22.753476