Author

Christine Leemann

University Hospital Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Karin Jutta MetzneriD· 2 shared Aathma Merin Bejoy· 1 shared Ali MovasatiiD· 1 shared Andreas BrunschweigeriD· 1 shared Helen Louise LightfootiD· 1 shared Jeffrey L. SchloßhaueriD· 1 shared Jochen ImigiD· 1 shared Jonathan HalliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersEvolutionary Biology

Karin Jutta MetznerORCID

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2 papers

Recent·Most cited

Evolutionary BiologyVirus EvolutionPeer-reviewedJan 1, 2026

Substantial Deceleration of Adaptation of HIV-1 Within 1,500 Generations in an Experimental Evolution: A Genomic Perspective

Ali Movasati, Christine Leemann, Kathrin Neumann…·Roland R. Regoes

This study tracks HIV-1 adaptation over 1,500 generations in human T-cell lines, finding a substantial deceleration in adaptive mutation fixation rates and fitness gains.

DOI 10.1093/ve/veag059

humanwhole-genome sequencing

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Molecular BiologybioRxivPreprintNov 10, 2024

Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-viral hsa-miR-132 Processing

Verena Schlösser, Helen Louise Lightfoot, Christine Leemann…·Jochen Imig

This study shows Enoxacin reduces HIV-1 replication by downregulating hsa-miR-132-3p in T-cells, suggesting potential for antiviral therapy through miRNA modulation.

DOI 10.1101/2024.11.10.622865

humanbulk RNA-seq

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