Claudia Hinze

This paper shows that rigid, bivalent CTLA-4 binding to CD80 disrupts the cis CD80/PD-L1 interaction, promoting PD-L1 availability through orientation and cross-linking.

This paper identifies Laminin 111 as a trigger for cellular quiescence and long-term survival through IQGAP1-mediated cytosolic scaffolding of ERK and BAD inactivation.