Cancer BiologyFrontiers in OncologyPeer-reviewed
Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs
Terri V Cornforth, Nathifa A. Moyo, Suzanne Cole…·Joseph D. Dukes
The paper shows that MR1-restricted TCRs recognize an allelic variant of MR1 (MR1*04) present in healthy individuals, indicating that these TCRs are not cancer-specific and may react to both cancer and healthy cells.
14 citations