NeurosciencebioRxivPreprint
Proteo-transcriptomic reprogramming and resource reallocation define the aging mammalian brain
Nisha Hemandhar-Kumar, Verena Kluever, Svenja V. Kaufmann…·Eugenio F. Fornasiero
This study identifies molecular signatures of aging in the mouse brain through proteo-transcriptomic analysis, revealing changes in protein aggregation, mRNA relocalization, and translation efficiency linked to neurodegeneration.
DOI 10.1101/2025.08.14.669896