NeuroscienceJournal of NeurosciencePeer-reviewed
A pathogenic missense mutation in kainate receptors elevates dendritic excitability and synaptic integration through dysregulation of SK channels
Toshihiro Nomura, Sakiko Taniguchi, Yizhi Wang…·Anis Contractor
This study investigates a missense mutation in the GRIK2 gene, showing it disrupts SK channel function, leading to increased dendritic excitability and synaptic integration in hippocampal neurons.
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