Author

D. A. Costantino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A.-L. Steckelberg· 2 shared J. C. Nix· 2 shared J. S. Kieft· 2 shared B. M. Akiyama· 1 shared Q. Vicens· 1 shared T. L. Sit· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

A.-L. Steckelberg

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2 papers

Recent·Most cited

BiochemistrybioRxivApr 30, 2020

The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold

A.-L. Steckelberg, Q. Vicens, D. A. Costantino…·J. S. Kieft

The paper presents the crystal structure of a polerovirus xrRNA, revealing sequence diversity within a conserved fold and explaining conservation patterns and new interactions.

DOI 10.1261/rna.076224.120

plant (other)structural biology

𝕏 PostBluesky

BiochemistrybioRxivFeb 9, 2018

A folded viral noncoding RNA blocks host cell exoribonucleases through programmed remodeling of RNA structure

A.-L. Steckelberg, B. M. Akiyama, D. A. Costantino…·J. S. Kieft

The paper identifies a novel RNA structure-dependent mechanism in dianthoviruses that blocks exoribonucleases, revealing convergent evolution of xrRNAs across unrelated viral families.

DOI 10.1073/pnas.1802429115

experimental assayhost-pathogen & immune response

𝕏 PostBluesky