Author

D. Acosta-Alvear

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Zappa· 2 shared J. C. Ponce-Rojas· 1 shared N. L. Muniozguren· 1 shared N. Lopez Muniozguren· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersCell Biology

F. Zappa

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 4, 2022

The integrated stress response induces a common cell-autonomous death receptor 5-dependent apoptosis switch

N. Lopez Muniozguren, F. Zappa, D. Acosta-Alvear

The paper shows the integrated stress response (ISR) triggers a cell-autonomous apoptosis mechanism via death receptor 5 under overwhelming stress.

DOI 10.1101/2022.07.04.498696

experimental assaycell signaling & trafficking

𝕏 PostBluesky

Cell BiologybioRxivNov 21, 2021

Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering

F. Zappa, N. L. Muniozguren, J. C. Ponce-Rojas, D. Acosta-Alvear

This study shows PKR signaling involves dynamic clusters that buffer downstream signaling, potentially enabling proofreading of the integrated stress response.

DOI 10.1083/jcb.202111100

experimental assaychromatin & epigenetic regulation

𝕏 PostBluesky