Cell BiologybioRxiv
Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering
F. Zappa, N. L. Muniozguren, J. C. Ponce-Rojas, D. Acosta-Alvear
This study shows PKR signaling involves dynamic clusters that buffer downstream signaling, potentially enabling proofreading of the integrated stress response.
DOI 10.1083/jcb.202111100