Author

D. B. Constam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. P. Nievergelt· 1 shared A. Pasquato· 1 shared A. Persat· 1 shared A. Radenovic· 1 shared A. Roulin· 1 shared B. Drake· 1 shared C. Brillard· 1 shared C. Fedeli· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiophysics

A. P. Nievergelt

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Author profile →

3 papers

Recent·Most cited

Time-resolved scanning ion conductance microscopy for three-dimensional tracking of nanoscale cell surface dynamics

S. M. Leitao, B. Drake, K. Pinjusic, X. Pierrat, V. Navikas, A. P. Nievergelt, C. Brillard, D. Djekic, A. Radenovic, A. Persat, D. B. Constam, J. Anders, G. E. Fantner

This paper introduces a time-resolved scanning ion conductance microscope (SICM) for high-speed, long-term nanoscale imaging of live cell surface dynamics with sub-5nm axial resolution.

bioRxiv · May 13, 2021Biophysics

A novel cell-based sensor detecting the activity of individual basic proprotein convertases

K. I. Low, K. Hardes, C. Fedeli, N. G. Seidah, D. B. Constam, A. Pasquato, T. Steinmetzer, A. Roulin, S. Kunz

The paper introduces PCific, a cell-based sensor to screen and distinguish inhibitors of individual basic proprotein convertases in mammalian cells.

bioRxiv · Nov 6, 2018Biochemistry

Paracrine Activin-A Signaling Promotes Melanoma Growth And Metastasis Through Immune Evasion

P. Donovan, O. A. Dubey, S. Kallioinen, K. W. Rogers, K. Muehlethaler, P. Mueller, D. Rimoldi, D. B. Constam

This study shows that paracrine Activin-A signaling in melanoma promotes tumor growth and metastasis by inhibiting anti-tumor immunity and causing muscle wasting.

bioRxiv · Jun 1, 2017Cancer Biology