Plasmin improves oedematous blood-gas barrier by cleaving epithelial sodium channels
R. Zhao, G. Ali, H.-G. Nie, Y. Chang, D. Bhattarai, X. Su, X. Zhao, M. A. Matthay, H.-L. Ji
This study shows plasmin cleaves ENaC channels at multiple sites, enhancing fluid clearance in lung injury models.
bioRxiv · Feb 9, 2020Pharmacology & Toxicology