Author

D. Bosch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Organism:zebrafish· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Koyunlar· 2 shared E. Bindels· 2 shared E. de Pater· 2 shared E. Gioacchino· 2 shared H. de Looper· 2 shared I. P. Touw· 2 shared J. Zink· 2 shared K. J. Gussinklo· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

C. Koyunlar

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2 papers

Recent·Most cited

GATA2 haploinsufficiency causes an epigenetic feedback mechanism resulting in myeloid and erythroid dysplasia

E. Gioacchino, W. Zhang, C. Koyunlar, J. Zink, H. de Looper, K. J. Gussinklo, R. Hoogenboezem, D. Bosch, E. Bindels, I. P. Touw, E. de Pater

This study shows that GATA2 haploinsufficiency in zebrafish leads to epigenetic feedback increasing Gata2b expression, causing myeloid and erythroid dysplasia through lineage differentiation defects.

bioRxiv · Oct 29, 2021 · PreprintCancer Biology

Single cell transcriptome analysis reveals an essential role for Gata2b in hematopoietic lineage decisions in zebrafish

E. Gioacchino, C. Koyunlar, H. de Looper, M. de Jong, T. Dobrzycki, R. Hoogenboezem, J. Zink, D. Bosch, P. van Strien, M. E. van Royen, P. French, E. Bindels, R. Monteiro, K. J. Gussinklo, I. P. Touw, E. de Pater

This study identifies Gata2b's role in myeloid-lymphoid lineage decisions in zebrafish using single-cell transcriptomics.

bioRxiv · Sep 4, 2019 · PreprintImmunology