Cancer BiologybioRxiv
Somatic Mutations Predict Acute Myeloid Leukemia Years Before Diagnosis
P. Desai, N. Mencia-Trinchant, O. Savenkov…·D. C. Hassane
This study identifies somatic mutations in peripheral blood that predict acute myeloid leukemia (AML) years before diagnosis, with TP53 mutations showing the strongest association and earliest onset.
DOI 10.1038/s41591-018-0081-z