Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutation
Y. Hovhannisyan, Z. Li, D. Callon, R. Suspene, V. Batoumeni, A. Canette, J. Blanc, H. Hocini, C. Lefebvre, N. El-Jahrani, A. L'honore, E. Kordeli, P. Fornes, J.-P. Concordet, G. Tachdjian, , O. Agbulut
This study shows that mitochondrial defects in desmin-mutated cardiomyocytes contribute to cardiomyopathy and can be reversed by transferring normal mitochondria.
bioRxiv · Sep 14, 2023 · PreprintPathology