Author

M. S. Deffieu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R. Gaudin· 3 shared E. Partiot· 2 shared A. Hirschler· 1 shared B. Bonaventure· 1 shared B. Charlot· 1 shared B. Pradel· 1 shared C. Bories· 1 shared C. Carapito· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

R. Gaudin

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Author profile →

3 papers

Recent·Most cited

LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes

B. Pradel, M. S. Deffieu, V. Robert-Hebmann, G. Cantaloube, M. Faure, N. Chazal, R. Gaudin, L. Espert

The paper shows HIV-1 uses LC3B conjugation to enhance its entry into CD4+ T cells, independent of autophagy.

bioRxiv · Jul 11, 2023Microbiology

Trans-synaptic dwelling of SARS-CoV-2 particles perturbs neural synapse organization and function

E. Partiot, A. Hirschler, S. Colomb, W. Lutz, T. Claeys, F. Delalande, M. S. Deffieu, J. Roels, J. Bons, D. Callon, L. Andreoletti, M. Labrousse, F. M. Jacobs, V. Rigau, B. Charlot, , R. Gaudin

The paper shows that SARS-CoV-2 exposure perturbs neural synapse organization and electrical activity by lodging at trans-synaptic interfaces.

bioRxiv · Sep 13, 2022 · PreprintMicrobiology

Pharmacological perturbation of intracellular dynamics as a SARS-CoV-2 antiviral strategy

W. Bakhache, E. Partiot, V. Lucansky, Y. Bare, B. Bonaventure, C. Goujon, C. Bories, M. S. Deffieu, R. Gaudin

This paper identifies RG10 and RG10b as potent antiviral compounds against SARS-CoV-2 by perturbing ER/virus dynamics, with RG10b showing improved stability and efficacy.

bioRxiv · Sep 10, 2021 · PreprintMicrobiology