Ablation of tanycytes of the arcuate nucleus and median eminence increases visceral adiposity and decreases insulin sensitivity in male mice.
S. Yoo, D. Cha, S. Kim, L. Jiang, M. Adebesin, A. Wolfe, R. Riddle, S. Aja, S. Blackshaw
This study shows that ablating tanycytes in male mice increases visceral fat and reduces insulin sensitivity, but not body weight or food intake.
bioRxiv · May 16, 2019Physiology