Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids allows access to masked epitopes in live neurons
D. Bessa-Neto, A. Kuhlemann, G. Beliu, V. Pecoraro, S. Doose, N. Retailleau, N. Chevrier, D. Perrais, M. Sauer, D. Choquet
The paper develops a method to label and image masked epitopes of transmembrane proteins in live neurons using non-canonical amino acids and genetic code expansion.
bioRxiv · Feb 27, 2021 · PreprintCell Biology