Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain
H. Yang, J. Pacheco, K. Kim, D. Ebrahimi, F. Ito, X. S. Chen
This study identifies how AA/GA dinucleotides downstream of target-C sites enhance APOBEC3G DNA editing through structural and biochemical analysis of rhesus macaque A3G.
bioRxiv · Mar 11, 2024Biochemistry