Author

D. Fails

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Mohan· 1 shared A. P. West· 1 shared B. Wang· 1 shared C. W. Tong· 1 shared G. S. Shadel· 1 shared J. D. Bryant· 1 shared J. Deng· 1 shared J. J. Vanportfliet· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Mohan

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1 paper

Recent·Most cited

Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

Y. Lei, J. J. Vanportfliet, Y.-F. Chen, J. D. Bryant, Y. Li, D. Fails, S. Torres Odio, K. B. Ragan, J. Deng, A. Mohan, B. Wang, O. Brahms, S. Yates, M. Spencer, C. W. Tong, , A. P. West

This study shows that ZBP1 and cGAS cooperate to detect mitochondrial DNA, leading to cardiotoxicity, and that blocking this interaction protects against heart damage.

bioRxiv · May 30, 2022Immunology