Author

D. Gianni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Clark· 1 shared A. M. Van Den Brink· 1 shared B. Bisnett· 1 shared C. H. Lamb· 1 shared D. R. Poyner· 1 shared D. Safitri· 1 shared E. A. Miller· 1 shared G. Ladds· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Clark

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2 papers

Recent·Most cited

Selective inhibition of protein secretion by abrogating receptor-coat interactions during ER export.

N. Gomez-Navarro, J. Maldutyte, K. Poljak, S.-Y. Peak-Chew, J. Orme, B. Bisnett, C. H. Lamb, M. Boyce, D. Gianni, E. A. Miller

The paper inhibits protein secretion by disrupting receptor-coat interactions, specifically targeting PCSK9 and other SURF4 clients without affecting other secreted proteins.

bioRxiv · Jan 31, 2022Cell Biology

CGRP-receptor family reveals endogenous GPCR agonist bias and its significance in primary human cardiovascular cells

A. Clark, N. Mullooly, D. Safitri, M. Harris, T. de Vries, A. M. Van Den Brink, D. R. Poyner, D. Gianni, M. Wigglesworth, G. Ladds

The paper demonstrates endogenous agonist bias at the calcitonin-like receptor in primary human cardiovascular cells, showing physiological consequences through RAMP switching.

bioRxiv · Dec 21, 2020 · PreprintPharmacology & Toxicology