Author

D. Gnutt

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Becker· 1 shared A. Brockmann· 1 shared A. K. C. Ulrich· 1 shared D. Bucher· 1 shared H. Stahlberg· 1 shared M. Botte· 1 shared M. Chami· 1 shared M. Hennig· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

A. Becker

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1 paper

Recent·Most cited

Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation

M. Botte, A. K. C. Ulrich, R. Adaixo, D. Gnutt, A. Brockmann, D. Bucher, M. Chami, N. Bocquet, U. Ebbinghaus-Kintscher, V. Puetter, A. Becker, U. Egner, H. Stahlberg, M. Hennig, S. J. Holton

This paper reports the cryo-EM structure of hTRPV4 in an open conformation induced by 4-PDD agonist, revealing molecular mechanisms of activation and providing a template for inhibitor design.

bioRxiv · Oct 13, 2020 · PreprintMolecular Biology