Author

D. Griffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Bardelli· 1 shared A. U. Lindner· 1 shared C. Graham· 1 shared C. J. Scott· 1 shared C. Jenkins· 1 shared C. Latimer· 1 shared C. Winnington· 1 shared E. E. Parkes· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Bardelli

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer.

H. Khawaja, R. Briggs, C. Latimer, M. Rassel, D. Griffin, L. Hanson, A. Bardelli, F. Di Nicolantonio, S. S. McDade, C. J. Scott, S. Lambe, M. Maurya, A. U. Lindner, J. H. M. Prehn, J. Sousa, , S. Van Schaeybroeck

This study identifies Bcl-xL as a mediator of resistance to KRASG12C inhibitors in colorectal cancer and shows that combining Bcl-xL inhibition with KRASG12C inhibition enhances apoptosis and reduces tumor growth.

bioRxiv · May 10, 2022Cancer Biology

Heparin MicroIslands for Spontaneous Gradient Formation and Improved Diabetic Wound Healing Outcomes

L. Pruett, C. Jenkins, N. Singh, K. Catallo, D. Griffin

This paper introduces heparin microislands to create chemotactic gradients for improved diabetic wound healing by enhancing cell migration and tissue regeneration.

bioRxiv · Oct 31, 2020Bioengineering

The clinical and molecular significance associated with STING signaling in estrogen receptor-positive early breast cancer

E. E. Parkes, M. P. Humphries, E. Gilmore, F. A. Sidi, V. Bingham, S. M. Phyu, S. G. Craig, C. Graham, J. Miller, D. Griffin, R. D. Kennedy, S. F. Bakhoum, S. McQuaid, M. Salto-Tellez, N. E. Buckley

The paper identifies perinuclear STING (pnSTING) in ER+ breast cancer as a prognostic marker linked to immune infiltration and poor outcomes in low pnSTING tumors.

bioRxiv · Jul 23, 2020Cancer Biology