Author

D. Herrmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. McFarland· 1 shared A. S. Cazet· 1 shared A. Swarbrick· 1 shared B. L. Elsworth· 1 shared C. Cooper· 1 shared C.-L. Chan· 1 shared D. N. Watkins· 1 shared D. Roden· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. McFarland

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Author profile →

3 papers

Recent·Most cited

Control of subunit stoichiometry in single-chain MspA nanopores

M. Pavlenok, L. Yu, D. Herrmann, M. Wanunu, M. Niederweis

This study converts octameric MspA into single-chain pores to improve DNA sequencing accuracy by enabling controlled subunit stoichiometry and pore geometry.

bioRxiv · Sep 25, 2021Biophysics

Structural basis for human T-cell leukemia virus type 1 Gag targeting to the plasma membrane for assembly

D. Herrmann, L. W. Zhou, H. M. Hanson, N. A. Willkomm, L. M. Mansky, J. S. Saad

This study determines the structural basis of HTLV-1 Gag targeting to the plasma membrane, showing that myr(-)MA binds to PI(4,5)P2 and PS through charge-charge interactions and a basic patch of lysine and arginine residues.

bioRxiv · Apr 8, 2021Microbiology

Targeting stromal remodeling and cancer stem cell plasticity to overcome chemoresistance in triple negative breast cancer

A. S. Cazet, M. N. Hui, B. L. Elsworth, S. Z. Wu, D. Roden, C.-L. Chan, J. N. Skhinas, R. Collot, J. Yang, K. Harvey, M. Z. Johan, C. Cooper, R. Nair, D. Herrmann, A. McFarland, , A. Swarbrick

This study identifies Hedgehog signaling to cancer-associated fibroblasts as a driver of cancer stem cell plasticity and chemoresistance in TNBC, showing that targeting this pathway with smoothened inhibitors improves survival in preclinical models and clinical trials.

bioRxiv · Nov 8, 2017Cancer Biology