M. Wanunu

Electro-Osmotic Flow Generation via a Sticky Ion Action

This study demonstrates a method to generate electro-osmotic flow using sticky ions, showing it works in both biological and solid-state nanopores.

Post-Transcriptional Methylation of Mitochondrial-tRNA Differentially Contributes to Mitochondrial Pathology

The paper shows that N1-methylation at position 9 of mt-Leu(UAA) stabilizes wild-type mt-tRNA but destabilizes pathogenic variants, suggesting methylation control could be therapeutic.

Synthesis of Long RNA with a Site-Specific Modification by Enzymatic Splint Ligation

This paper improves the synthesis of long RNA with site-specific modifications using enzymatic splint ligation by addressing structural and sequence heterogeneity.

High-Voltage Biomolecular Sensing Using a Bacteriophage Portal Protein Covalently Immobilized Within a Solid-State Nanopore

This paper develops a hybrid nanopore by covalently linking a bacteriophage portal protein to a solid-state nanopore, enhancing stability and enabling high-voltage DNA sensing and sequencing.

Unidirectional Single-File Transport of Full-Length Proteins Through a Nanopore

This paper demonstrates a method for unidirectional transport of full-length proteins through nanopores using guanidinium chloride and machine learning to identify protein orientation and identity.

Control of subunit stoichiometry in single-chain MspA nanopores

This study converts octameric MspA into single-chain pores to improve DNA sequencing accuracy by enabling controlled subunit stoichiometry and pore geometry.

CMOS electrochemical imaging arrays for thedetection and classification of microorganisms

This paper introduces CMOS electrochemical imaging arrays for detecting and classifying microorganisms in their natural environments.

Electrical Unfolding of Cytochrome c During Translocation Through a Nanopore Constriction

This paper investigates how electric fields affect the translocation of cytochrome c through nanopores of different diameters, showing that electric fields can stabilize unfolded states and influence translocation modes.

Stable Polymer Bilayers for Protein Channel Recordings at High Guanidinium Chloride Concentrations

This paper demonstrates that polymer bilayers are stable and leak-free at high guanidinium chloride concentrations, enabling reliable protein channel recordings.