Author

D. Holtzman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

A. Feldhaus· 1 shared A. G. CASHIKAR· 1 shared B. Fiala· 1 shared C. Wolf· 1 shared D. Ellis· 1 shared D. T. Rios· 1 shared D. Timm· 1 shared J. L. McKechnie· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Feldhaus

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Virus-like particle displaying SARS-CoV-2 receptor binding domain elicits neutralizing antibodies and is protective in a challenge model

J. L. McKechnie, B. Fiala, C. Wolf, D. Ellis, D. Holtzman, A. Feldhaus

This study develops a virus-like particle vaccine, IVX-411, that elicits neutralizing antibodies and provides protection against multiple SARS-CoV-2 variants in a challenge model.

bioRxiv · Nov 29, 2022 · PreprintImmunology

Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol

A. G. CASHIKAR, D. T. Rios, D. Timm, J. Romero, J. Long, X. Han, D. Holtzman, S. M. Paul

This study shows that 25-hydroxycholesterol from microglia alters astrocyte lipid metabolism and ApoE secretion through mechanisms involving LXRs, Abca1, and Cyp7b1.

bioRxiv · May 3, 2022Cell Biology