MICROGLIAL CELL EXPRESSION OF THE TYPE 2 CANNABINOID RECEPTOR REGULATES IMMUNE-MEDIATED NEUROINFLAMMATION
A. Moe, A. Rayasam, G. Sauber…·W. Drobyski
This study shows that CB2R on microglia drives neuroinflammation in GVHD by promoting T cell activation and neuronal death, and that targeting CB2R reduces inflammation without worsening systemic GVHD.