Author

J. L. McKechnie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. Arauz· 2 shared C. A. Blish· 2 shared D. Beltran· 2 shared L. Saenz· 2 shared R. Vergara· 2 shared S. Lopez-Verges· 2 shared A. Feldhaus· 1 shared A. Pitti· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

A. B. Arauz

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 29, 2022

Virus-like particle displaying SARS-CoV-2 receptor binding domain elicits neutralizing antibodies and is protective in a challenge model

J. L. McKechnie, B. Fiala, C. Wolf…·A. Feldhaus

This study develops a virus-like particle vaccine, IVX-411, that elicits neutralizing antibodies and provides protection against multiple SARS-CoV-2 variants in a challenge model.

DOI 10.1101/2022.11.29.518404

mousevirus

𝕏 PostBluesky

ImmunologybioRxivJul 27, 2020

Mass cytometry analysis of the NK cell receptor-ligand repertoire reveals unique differences between dengue-infected children and adults

J. L. McKechnie, D. Beltran, A.-M. M. Ferreira…·C. A. Blish

This study uses mass cytometry to compare NK cell receptor-ligand profiles between dengue-infected children and adults, identifying distinct immune signatures associated with infection outcomes.

DOI 10.4049/immunohorizons.2000074

humanflow cytometry

𝕏 PostBluesky

ImmunologybioRxivJul 11, 2019

HLA upregulation during dengue virus infection suppresses the natural killer cell response

J. L. McKechnie, D. Beltran, A. Pitti…·S. Lopez-Verges

This study shows that HLA class I upregulation during dengue virus infection suppresses natural killer cell activity, potentially contributing to disease progression.

DOI 10.3389/fcimb.2019.00268

humanexperimental assay

𝕏 PostBluesky