Author

D. Imoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Toda· 2 shared H. Matsunaga· 2 shared I. Yamamoto· 2 shared K. Kimura· 2 shared M.-L. Lee· 2 shared N. Iijima· 2 shared S. Sawai· 2 shared A. Kamiya· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPhysiology

C. Toda

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Random walk and cell morphology dynamics in Naegleria gruberi

M. Uwamichi, Y. Miura, A. Kamiya, D. Imoto, S. Sawai

This study quantifies the movement and morphology dynamics of Naegleria gruberi, showing it behaves as a persistent random walker with two time-scales similar to Dictyostelium and neutrophils.

bioRxiv · Aug 25, 2023 · PreprintCell Biology

Comparative mapping of crawling-cell morphodynamics in deep learning-based feature space

D. Imoto, N. Saito, A. Nakajima, G. Honda, M. Ishida, T. Sugita, S. Ishihara, K. Katagiri, C. Okimura, Y. Iwadate, S. Sawai

The paper maps crawling-cell morphodynamics in a deep learning-based feature space using phase-field modeling and identifies key parameters for migratory morphologies under perturbations.

bioRxiv · Sep 6, 2020Cell Biology

Activation of prodynorphin neurons in the dorsomedial hypothalamus inhibits food intake and promotes positive valence

D. Imoto, I. Yamamoto, H. Matsunaga, T. Yonekura, M.-L. Lee, K. X. KATO, T. Yamasaki, K.-i. Otsuguro, M. Horiuchi, N. Iijima, K. Kimura, C. Toda

The paper identifies refeeding-responsive neurons in the dorsomedial hypothalamus that reduce food intake and enhance positive valence when activated.

bioRxiv · Jul 2, 2020 · PreprintPhysiology

Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism

M.-L. Lee, H. Matsunaga, Y. Sugiura, T. Hayasaka, I. Yamamoto, D. Imoto, M. Suematsu, N. Iijima, K. Kimura, S. Diano, C. Toda

This study shows that cPLA2-mediated phospholipid metabolism in the VMH regulates glucose metabolism under RCD but worsens it under HFD through changes in insulin sensitivity and inflammation.

bioRxiv · May 18, 2020Physiology