Pharmacology & ToxicologybioRxiv
Discovery of a celecoxib binding site on PTGES with a cleavable chelation-assisted biotin probe
D. K. Miyamoto, H. A. Flaxman, H.-Y. Wu…·C. M. Woo
This paper identifies a new celecoxib binding site on PTGES using a cleavable chelation-assisted biotin probe and validates it through competitive displacement and structural modeling.
DOI 10.1021/acschembio.9b00511