Author

D. Karachentsev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Becker· 1 shared B. Ozcan· 1 shared C. Hopf· 1 shared D. Gomes Moreira· 1 shared K. M. Zoltowska· 1 shared L. Chavez-Gutierrez· 1 shared M. C. Houser· 1 shared M. L. Franco· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Becker

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

K. M. Zoltowska, U. Das, S. Lismont, T. Enzlein, M. Maesako, M. C. Houser, D. Gomes Moreira, M. L. Franco, B. Ozcan, D. Karachentsev, A. Becker, C. Hopf, M. Vilar, O. Berezovska, W. Mobley, L. Chavez-Gutierrez

This study shows that human Aβ42 inhibits γ-secretase, leading to substrate accumulation and neuronal dysfunction, suggesting a feedback mechanism in Alzheimer's disease.

bioRxiv · Aug 2, 2023Biochemistry