U. Das

A novel repressor-activator-competitor module comprising C2H2 zinc finger and NAC transcription factors regulates rice grain development

This study identifies a repressor-activator-competitor module involving ZOS1-15 and ONAC024 that regulates rice grain development through interactions with other transcription factors and co-repressors.

Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice

This study shows that disrupting the PGE2 synthesis or response pathway reduces atherogenesis in PD-1 deficient hyperlipidemic mice through different immune mechanisms.

Epigenetic Control of Adaptive or Homeostatic Splicing of Alternative Exons and Prolactin Gene Expression During Interval-Training Activities of Pituitary Cells

This study shows that interval-training depolarization of pituitary cells triggers adaptive or homeostatic splicing of alternative exons, regulated by DNA methylation and MeCP2, while maintaining steady Prolactin gene expression.

5-Aza-Cytidine Enhances Terminal Polyadenylation Site Usage for Full-Length Transcripts in Cells

This study shows 5-aza-cytidine promotes terminal polyadenylation site usage, increasing full-length transcripts in cancer cells by altering poly(A) site selection and related factors.

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

This study shows that human Aβ42 inhibits γ-secretase, leading to substrate accumulation and neuronal dysfunction, suggesting a feedback mechanism in Alzheimer's disease.

Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing in vitro and in vivo zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells

This paper introduces self-transfecting GMO-PMO chimeras for gene silencing, showing effectiveness in zebrafish and cancer cell inhibition of NANOG, enhancing therapeutic potential.

Demonstration of altruistic behaviour in rats

This study shows rats can act altruistically by voluntarily distressing themselves to help others without expecting rewards.