High-throughput screening for Cushing's disease: therapeutic potential of thiostrepton via cell cycle regulation
T. Hakata, I. Yamauchi, D. Kosugi, T. Sugawa, H. Fujita, K. Okamoto, Y. Ueda, T. Fujii, D. Taura, N. Inagaki
This study identifies thiostrepton as a potential therapy for Cushing's disease by inducing cell cycle arrest in PitNETs through mechanisms independent of FOXM1.
bioRxiv · Feb 22, 2024Cell Biology