T. Kita

This study characterizes KIF1Bβ motor activity using single-molecule assays and C. elegans genetics, showing reduced activity due to a disease mutation.

This study analyzes the transcriptome of hyperthyroid mice overexpressing TSH, identifying novel genes and pathways associated with goiter development and thyroid hormone secretion.

This paper develops mathematical models to explain the motility of KIF1A heterodimers, showing that a coordinated head model better predicts experimental results than an independent head model.

This study compares KLP-6 and UNC-104, two Caenorhabditis elegans kinesin-3 proteins, revealing that autoinhibition release triggers dimerization and processive movement in UNC-104 but not in KLP-6.

The paper reports the crystal structure of KLP-12-tubulin complex, revealing how KLP-12 inhibits microtubule dynamics by altering tubulin curvature.

This study establishes C. elegans models for KIF1A-associated neuronal disorder and shows that disease mutations inhibit wild-type KIF1A function in heterodimers.