Author

D. L. Kober

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Baban· 1 shared C. E. Kluender· 1 shared C. Frieden· 1 shared D. F. Steinberg· 1 shared D. M. Holtzman· 1 shared D. Rosenbaum· 1 shared E. D. Roberson· 1 shared H. B. Dean· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

B. Baban

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Author profile →

2 papers

Recent·Most cited

Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo

D. L. Kober, M. C. Caballero Van Dyke, J. L. Eitson, I. N. Boys, M. B. McDougal, D. Rosenbaum, J. W. Schoggins

This paper develops a mutant ACE2 that neutralizes SARS-CoV-2 in vivo through aerosolized delivery, demonstrating its protective effect in a mouse model.

bioRxiv · Sep 26, 2023Microbiology

Functional insights from biophysical study of TREM2 interactions with ApoE and Aβ1-42

D. L. Kober, M. D. Stuchell-Brereton, C. E. Kluender, H. B. Dean, M. R. Strickland, D. F. Steinberg, S. S. Nelson, B. Baban, D. M. Holtzman, C. Frieden, J. M. Alexander-Brett, E. D. Roberson, Y. Song, T. J. Brett

This study investigates TREM2 interactions with ApoE and Aβ1-42 using biophysical methods, revealing distinct binding surfaces and a potential role for sTREM2 in inhibiting Aβ polymerization.

Alzheimer's & Dementia · Oct 8, 2020Peer-reviewedBiophysics