Cancer BiologybioRxiv
Hypoxia-induced activation of NDR2 underlies brain metastases from Non-Small Cell Lung Cancer
J. Levallet, T. Biojout, C. Bazille…·G. Levallet
This study identifies hypoxia-induced NDR2 activation as a driver of brain metastases in NSCLC, showing NDR2 overexpression correlates with metastatic potential and can be measured via immunohistochemistry.
DOI 10.1038/s41419-023-06345-3