Mechanosensitive dynamics of lysosomes along microtubules regulate leader cell emergence in collective cell migration
R. Marwaha, S. Rawal, P. Khuntia, S. Banerjee, D. Manoj, M. Jaiswal, T. Das
The paper identifies lysosomal dynamics along microtubules as critical for leader cell emergence in collective cell migration by modulating Rac1 activity and actin polymerization.
bioRxiv · Aug 3, 2022 · PreprintCell Biology