Smad4 Loss in the Mouse Intestinal Epithelium Alleviates the Pathological Fibrotic Response to Injury in the Colon
Z. Hashemi, T. Hui, A. Wu, D. Matouba, S. Zokowski, S. Nejati, C. Lim, J. Bruzzese, K. Seabold, C. Mills, C. Lin, K. Wrath, H. Wang, H. Wang, M. P. Verzi, A. Perekatt
This study shows that Smad4 loss in the mouse intestinal epithelium reduces pathological fibrosis and improves mucosal repair after DSS-induced injury.
bioRxiv · Mar 8, 2024 · PreprintCell Biology