Macrophages protect against loss of adipose tissue during cancer cachexia
M. Erdem, D. Moeckel, S. Jumpertz, C. John, A. Fragoulis, I. Rudolph, J. Wulfmeier, J. Springer, H. Horn, M. Koch, G. Lurje, T. Lammers, G. van der Kroft, F. Gremse, T. Cramer
This study shows that defective myeloid cell-mediated inflammation enhances cachexia in HCC mice, suggesting macrophages protect against fat loss in cancer cachexia.
bioRxiv · Sep 27, 2018Cancer Biology