A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity
M. Alexander, V. Upadhyay, R. Rock, L. Ramirez, K. Trepka, P. Puchalska, D. Orellana, Q. Y. Ang, C. Whitty, J. A. Turnbaugh, Y. Tian, D. Dumlao, R. R. Nayak, A. D. Patterson, J. C. Newman, , P. J. Turnbaugh
This study shows that a ketogenic diet reduces autoimmune disease in mice by altering host metabolism and shaping gut microbiota, specifically through β-hydroxybutyrate and Lactobacillus species.
bioRxiv · Nov 2, 2023Microbiology