Author

K. Trepka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

P. J. Turnbaugh· 3 shared M. Alexander· 2 shared A. D. Patterson· 1 shared A. Foye· 1 shared A. Heinken· 1 shared B. DeFelice· 1 shared C. Noecker· 1 shared C. Whitty· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

P. J. Turnbaugh

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity

M. Alexander, V. Upadhyay, R. Rock, L. Ramirez, K. Trepka, P. Puchalska, D. Orellana, Q. Y. Ang, C. Whitty, J. A. Turnbaugh, Y. Tian, D. Dumlao, R. R. Nayak, A. D. Patterson, J. C. Newman, , P. J. Turnbaugh

This study shows that a ketogenic diet reduces autoimmune disease in mice by altering host metabolism and shaping gut microbiota, specifically through β-hydroxybutyrate and Lactobacillus species.

bioRxiv · Nov 2, 2023Microbiology

Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors

T. S. Kyaw, M. Sandy, K. Trepka, J. Goh, K. Yu, V. Dimassa, E. Bess, J. Bisanz, P. J. Turnbaugh

The gut bacterium Eggerthella lenta secretes inhibitors of P-glycoprotein ATPase activity, accelerating drug absorption.

bioRxiv · Oct 13, 2022Microbiology

Systems biology illuminates alternative metabolic niches in the human gut microbiome

C. Noecker, J. Sanchez, J. E. Bisanz, V. Escalante, M. Alexander, K. Trepka, A. Heinken, Y. Liu, D. Dodd, I. Thiele, B. DeFelice, P. J. Turnbaugh

This study identifies the metabolic niche of Eggerthella lenta in the human gut by combining experimental and computational approaches, revealing its use of acetate and arginine catabolism.

bioRxiv · Sep 19, 2022 · PreprintMicrobiology

CUB domain containing protein 1 (CDPC1) is a target for radioligand therapy in castration resistant prostate cancer

N. Zhao, k. Trepka, Y.-h. Wang, S. Chopra, N. Hooshdaran, H. Kim, J. Yang, J. Zhuo, S. Lim, K. K. Leung, E. Egusa, L. K. Zhang, A. Foye, J. Chou, F. Y. Feng, , R. Aggarwal

This paper evaluates CDCP1 as a target for radioligand therapy in mCRPC, showing its expression in most biopsies and demonstrating antitumor effects with 177Lu-4A06.

bioRxiv · Jun 17, 2021 · PreprintCancer Biology

Modifying reaction diffusion: A numerical model for Turing morphogenesis and Ben Jacob patterns

K. Trepka

The paper develops a discrete numerical reaction-diffusion model to simulate animal pattern formation and Ben-Jacob bacterial growth.

bioRxiv · Apr 11, 2020 · PreprintBiophysics