MicrobiologybioRxiv
Paradoxical activation of a type VI secretion system (T6SS) phospholipase effector by its cognate immunity protein
S. J. Jensen, Z. C. Ruhe, A. Williams…·C. S. Hayes
The paper identifies that disruption of the tli immunity gene in Enterobacter cloacae leads to hyper-permeability via unopposed Tle phospholipase activity, revealing distinct roles for Tli based on its subcellular localization.
DOI 10.1128/jb.00113-23