LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry.
Y. Yang, H. Chen, R. Corey, V. Morales, Y. Quentin, C. Froment, A. Caumont-Sarcos, C. Albenne, O. Burlet-Schiltz, D. Ranava, P. J. Stansfeld, J. Marcoux, R. Ieva
This study identifies LptM as a conserved lipoprotein that facilitates oxidative maturation of the LPS translocon by mimicking LPS binding, enabling efficient disulfide bond formation in LptD.
bioRxiv · Jan 2, 2023Microbiology