Author

V. Morales

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:bacteria (other)· 2 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Caumont-Sarcos· 2 shared C. Albenne· 2 shared D. Ranava· 2 shared P. Polard· 2 shared R. Ieva· 2 shared Y. Yang· 2 shared A. B. Dalia· 1 shared A.-L. Soulet· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

A. Caumont-Sarcos

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Author profile →

6 papers

Recent·Most cited

BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress

C. Sepulveda, M. Milani, V. Morales, G. Tamburini, N. Montes, C. Hetz

This study shows that BAX and BAK deficiency increases ER stress threshold for XBP1 splicing and reduces RIDD substrate degradation and IRE1 phosphorylation.

bioRxiv · Mar 26, 2024 · PreprintCell Biology

Two D-loop resolution systems enable natural genetic transformation in bacteria

L. Hardy, V. Morales, C. J. Rousseau, M. Berge, J. Plantade, F. Mazzamurro, T. N. Dalia, A. B. Dalia, E. P. C. Rocha, X. Charpentier, P. Polard

This study identifies two D-loop resolution systems in bacteria, YraN/ComM and CoiA/RadA, that work together to process the transformation D-loop during natural genetic transformation.

bioRxiv · Feb 6, 2024Microbiology

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

G. Contento, J.-A. A. Wilson, B. Selvarajah, M. Plate, D. Guillotin, V. Morales, M. Trevisani, V. Pitozzi, K. Bianchi, R. C. Chambers

This study shows that pyruvate metabolism affects fibroblast response to GLS1 inhibition during fibrosis, suggesting combined targeting of pyruvate metabolism and glutaminolysis as a therapeutic strategy.

bioRxiv · Jan 30, 2024Cell Biology

LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry.

Y. Yang, H. Chen, R. Corey, V. Morales, Y. Quentin, C. Froment, A. Caumont-Sarcos, C. Albenne, O. Burlet-Schiltz, D. Ranava, P. J. Stansfeld, J. Marcoux, R. Ieva

This study identifies LptM as a conserved lipoprotein that facilitates oxidative maturation of the LPS translocon by mimicking LPS binding, enabling efficient disulfide bond formation in LptD.

bioRxiv · Jan 2, 2023Microbiology

Assembly mechanism and cryoEM structure of RecA recombination nucleofilaments from Streptococcus pneumoniae.

M. Hertzog, T. N. Perry, P. Dupaigne, S. Serres, V. Morales, A.-L. Soulet, J. Bell, E. Margeat, S. C. Kowalczykowski, E. Le Cam, R. Fronzes, P. Polard

This study characterizes the ATP-dependent assembly mechanism and cryoEM structure of RecA nucleofilaments from Streptococcus pneumoniae, revealing differences in ssDNA binding and HR activity compared to Escherichia coli.

bioRxiv · Jul 28, 2022 · PreprintMicrobiology

Outer membrane lipoprotein DolP interacts with the BAM complex and promotes fitness during envelope stress response

D. Ranava, Y. Yang, L. Orenday-Tapia, F. Rousset, C. Turlan, L. Cui, V. Morales, C. Moulin, G. Munoz, J. Rech, A. Caumont-Sarcos, C. Albenne, D. Bikard, R. Ieva

The paper identifies DolP as an interactor of the BAM complex that enhances bacterial fitness during envelope stress by counteracting excessive BAM accumulation.

bioRxiv · Sep 23, 2020Microbiology